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Neurophysiology of Hypothalamic Peptidergic Neurons

  • L. P. Renaud
  • Q. J. Pittman
  • H. W. Blume
Part of the Published Nobel Symposia book series (NOFS, volume 42)

Abstract

Recent developments in radioimmunoassay, immunohistochemistry and biochemistry indicate that ‘peptidergic’ neurons constitute a significant portion of the cells of the central, peripheral and autonomic nervous systems. From an historical perspective, central peptidergic neurons have been traditionally associated with the hypothalamus, one of the few areas where they can be identified and examined with electrophysiological techniques. The information provided by these investigations has enhanced our understanding and appreciation of neural participation in the endocrine system, and has provoked other studies related to the role of peptides in interneuronal communication. This chapter will consider these issues as related to the neurophysiology of two groups of access-able putative peptidergic neurons of the hypothalamus i.e. neurohypophyseal and tuberoinfundibular neurons.

Keywords

Paraventricular Nucleus Median Eminence Supraoptic Nucleus Axon Collateral Recurrent Inhibition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1979

Authors and Affiliations

  • L. P. Renaud
    • 1
  • Q. J. Pittman
    • 1
  • H. W. Blume
    • 1
  1. 1.Division of NeurologyMontreal General HospitalMontrealCanada

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