Asymmetric Synthesis via Boranes: Chiral Allenic Boranes and Trialkylborane Reducing Agents

  • M. Mark Midland


Our research has been involved in the development and application of reactions of organoboranes, especially those which lead to chiral products. Organoboranes are well known for their ability to transform the alkyl group into various products with complete retention of configuration of the boron-carbon bond (eq 1).1 Likewise, chiral boranes, such as diisopinocampheylborane, may be used to induce optical activity during the hydroboration process (eq 2).2


Optical Purity Asymmetric Synthesis Enantiomeric Purity Asymmetric Reduction Phenyl Ketone 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • M. Mark Midland
    • 1
  1. 1.Department of ChemistryUniversity of CaliforniaRiversideUSA

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