Reproduction in Single-Sex Chimeras

  • Anne McLaren
Part of the Basic Life Sciences book series (BLSC, volume 12)


Chimeras can be either of mixed chromosomal sex, XX ↔ XY, or they can be single-sex, XX ↔ XX or XY ↔ XY. If the sex ratio at the time of chimera formation is unity, mixed-sex and single-sex chimeras will be expected to occur in equal numbers. The data available from chromosomal sexing of chimera components suggest that this expectation is fulfilled (McLaren 1976). The problems of XX ↔ XY animals, both from the point of view of sexual differentiation, and as regards the fate of their germ cells, are considered elsewhere in this volume. In this paper I shall restrict myself to single-sex chimeras and their germ cells.


Germ Cell Sertoli Cell Sperm Head Chimeric Mouse Strain Combination 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Anne McLaren
    • 1
  1. 1.MRC Mammalian Development Unit, Wolfson HouseUniversity College LondonLondonEngland

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