I would like to make a comment about Dr. Germaine’s work. We have determined that of all the salivary proteins, salivary or serum albumin is one of the most resistant to attack by proteolytic enzymes. Our findings explained the results published by Drs. Holt and Mestecky, who found an unusually large amount of immunologically intact albumin in dental plaque. Some of the most susceptible salivary proteins are the proline rich proteins as we presented yesterday. I would also like to make a comment about Dr. Mandel’s second paper. Several investigators have found an increase in β2-microglobulin in diseases affecting the parotid gland. It is believed that these proteins are released by lymphocytes which have migrated into the area. I was wondering whether you have measured β2-microglobulin levels in the various diseases.
KeywordsSalivary Protein Secretory Component Proline Rich Protein Parotid Saliva Active Caries
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