Preliminary Results in the Immunization of Irus Monkeys Against Dental Caries

  • Hans-J. Schick
  • Franz J. Klimek
  • Ernst Weinmann
  • Oswald Zwisler
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 107)


Studies utilizing gnotobiotic rodents have clearly shown that certain bacteria including Streptococcus mutans can induce dental caries (1–3). Since caries is an infectious disease, it is not surprising that recent efforts have been made to control this disease, especially in light of successful vaccines developed for other infectious diseases caused by bacteria (for a survey, see 4). Most studies of caries immunity have been performed in rodents.


Colony Form Unit Dental Caries Carious Lesion Plaque Index Oral Biol 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Hans-J. Schick
    • 1
  • Franz J. Klimek
    • 1
  • Ernst Weinmann
    • 1
  • Oswald Zwisler
    • 1
  1. 1.Behringwerke AG and Phillips UniversityMarburgGermany

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