Fimbriae of Actinomyces Viscosus T14V: Their Relationship to the Virulence-Associated Antigen and to Coaggregation with Streptococcus Sanguis 34

  • John O. Cisar
  • Floyd C. McIntire
  • Albert E. Vatter
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 107)


Actinomyces viscosus and the closely related A. naeslundii are plaque bacteria and have been implicated in the etiology of root surface caries and periodontal disease in experimental animals and in man (1–5). The specialized cell surface features which equip these microorganisms for life in the oral cavity are just beginning to be understood. An early clue was the finding of a fibrillar layer (i.e., fimbriae) on the cell surface of both organisms (6). Subsequent studies have provided electron microscopic evidence for participation of these structures in adherence to oral streptococci (7) and to epithelial cells (8).


Periodontal Disease Cell Wall Polysaccharide Oral Streptococcus Adherence Phenomenon Galactosyl Residue 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • John O. Cisar
    • 1
    • 2
    • 3
  • Floyd C. McIntire
    • 1
    • 2
    • 3
  • Albert E. Vatter
    • 1
    • 2
    • 3
  1. 1.Laboratory of Microbiology and ImmunologyNational Institute of Dental ResearchBethesdaUSA
  2. 2.Department of Oral Biology and PathologyUniversity of Colorado Medical CenterDenverUSA
  3. 3.Department of the Webb-Waring Lung InstituteUniversity of Colorado Medical CenterDenverUSA

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