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Genetic Alterations of Streptococcus Mutans’ Virulence

  • Jason M. Tanzer
  • Michael L. Freedman
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 107)

Abstract

Our laboratory has pursued the study of mutants of Streptococcus mutans with characterized phenotypic defects to assess the significance of specific traits in the causation of caries at various tooth surfaces. We have devised and executed mutant selection schemes yielding isolates defective in putatively important virulence characteristics. We have then conducted biochemical, physiological, and morphological studies, as well as assays of the virulence of these mutants, in comparison with their unaltered wild type (WT) progenitors.

Keywords

Dental Caries Plaque Formation Tooth Surface Streptococcus Mutans Blue Dextran 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Jason M. Tanzer
    • 1
  • Michael L. Freedman
    • 1
  1. 1.Department of Oral DiagnosisUniversity of Connecticut Health CenterFarmingtonUSA

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