A Common Mucosal Immunologic System Involving the Bronchus, Breast and Bowel

  • John Bienenstock
  • Mark McDermott
  • Dean Befus
  • Michael O’Neill
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 107)


The immune response of the upper respiratory tract is characterized by a predominance of secretory IgA anitbody in local secretions and IgA containing cells in the lamina propria (1). The amount of IgA which is present at various levels of the respiratory tract differs since much more IgA is found high, than low, in the respiratory tract (2). The amount of IgA relative to IgG diminishes in secretions derived from lower in the tract, so that washings derived from the alveolar spaces show a ratio of the two immunoglobulins which approximates that of serum (2).


Lamina Propria Mesenteric Node Peripheral Node Oral Immunization Mucosal Site 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • John Bienenstock
    • 1
  • Mark McDermott
    • 1
  • Dean Befus
    • 1
  • Michael O’Neill
    • 1
  1. 1.Host Resistance ProgramMcMaster UniversityHamiltonCanada

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