Cell Mediated Immune Responses to Bacterial Antigens on Human Mucosal Surfaces

  • M. Drucker
  • I. Drucker
  • E. Neter
  • J. Bernstien
  • P. L. Ogra
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 107)


Recently, the in vitro correlates of cell-mediated immunity to viral antigens have been demonstrated in human tonsillar tissue lymphocytes (TTL) and peripheral blood lymphocytes (PBL) (1,2). It has been suggested that human TTL respond differently from PBL to purified protein derivative (PPD) and mitogens (3). Human PBL have been stimulated by oral bacterial antigens and increased responses have been observed in subjects with chronic oral infections such as gingivitis or periodontitis (4,5).


Proliferative Activity Peripheral Blood Lymphocyte Proliferative Response Tetanus Toxoid Stimulation Index 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • M. Drucker
    • 1
    • 2
  • I. Drucker
    • 1
    • 2
  • E. Neter
    • 1
    • 2
  • J. Bernstien
    • 1
    • 2
  • P. L. Ogra
    • 1
    • 2
  1. 1.Departments of Pediatrics and MicrobiologyState University of New York at BuffaloBuffaloUSA
  2. 2.Divisions of Infectious Disease, Virology, and BacteriologyChildren’s HospitalBuffaloUSA

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