Lymphatic Physiology and Secretory Immunity
The chyle-filled lacteals of the mesentery, and the various components of the gut-associated lymphoid tissue (GALT) were noted by the earliest anatomists, but their role in mucosal immunity became apparent relatively recently and is still a somewhat controversial topic. It is true, unfortunately, that even amongst mammals, differences in reproductive and digestive physiology and age-related changes in the GALT make a general understanding of the immune systems of their various mucosae particularly difficult. Therefore, it may be helpful to review briefly some of the factors which are thought to govern the behaviour of those lymphoid cells and humoral factors that are associated with immune reactions at mucous surfaces.
KeywordsLamina Propria Interstitial Fluid Mesenteric Node Small Lymphocyte Secretory Component
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- 1.Thomas, H. C. and Vaez-Zadek, F., Immunol. 26: 375, 1974.Google Scholar
- 8.Reynolds, J., in The Gut-Associated Lymphoid System in Lambs, Ph.D. Thesis, Australian National University, Canberra, 1976.Google Scholar
- 13.Dineen, J. K. and Adams, D. B., Immunol. 19: 11, 1970.Google Scholar
- 15.Binns, R. M. and Hall, J. G., Br. J. Exp. Path. 47: 275, 1968.Google Scholar
- 33.Orlans, E., Peppard, J., Reynolds, J. and Hall, J. G., J. Exp. Med., in press.Google Scholar
- 36.Heremans, J. F., in The Antigens (Edited by Sela, M.), Vol. II, Academic Press, New York, 1974.Google Scholar
- 38.Porter, P., Noakes, D. E. and Allen, W. D., Immunol. 18: 909, 1970.Google Scholar