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Discussion

  • Jerry R. McGhee
  • Jiri Mestecky
  • James L. Babb
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 107)

Abstract

I would like to ask a question of Dr. Lally. You tried to see various kinds of T-cell effects on the IgA response engendered by splenic cells. I was wondering if you have tried the effect of carrier-primed suppressor cells made in the Tada manner. We found that transfer of Peyer’s patch cells resulted in an IgA response and it was T-cell dependent. When we looked at the effect of T cells that were generated to be suppressive, we found that of all the responsives, the IgA response was least affected. However, spleen IgA precursors seem more primary than those from Peyer’s patches. One might predict then, that kinds of splenic cells that are generating these IgA responses, might be more likely to be suppressed. Have you looked at this?

Keywords

Splenic Cell Lipoid Pneumonia Selection Phenomenon Secretory Immunity Main Fermentor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Jerry R. McGhee
    • 1
  • Jiri Mestecky
    • 1
  • James L. Babb
    • 1
  1. 1.Institute of Dental Research, Departments of Microbiology and Medicine, Comprehesive Cancer CenterUniversity of Alabama in BirminghamBirminghamUSA

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