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Hereditary Disorders of Intestinal Transport

  • M. D. Milne
Part of the Biomembranes book series (B, volume 4B)

Abstract

Hereditary abnormalities of intestinal transport are rare conditions but are of disproportionate importance because of the information they give regarding the mechanisms of intestinal absorption in man. The main disability is usually diarrhoea, but there may be abnormalities from lack of absorption of an essential nutrient or occasionally from absorption of compounds in excess due to failure of a normal control mechanism. These diseases are experiments of nature which cannot be exactly simulated in the laboratory animal, and thus may on occasions give information unobtainable from other sources. More often, however, they confirm that the mechanisms of absorption studied in detail in smaller mammals are probably applicable to man. In some of these diseases there is an associated defect of transport in the proximal renal tubules as well as in the gut. They furnish evidence, therefore, that transport processes are closely related in the gut and in the kidney, or at least that an important step in transport is identical at the two sites.

Keywords

Free Amino Acid Lactase Deficiency Autosomal Recessive Disease Megaloblastic Anaemia Hereditary Disorder 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1974

Authors and Affiliations

  • M. D. Milne
    • 1
  1. 1.Westminster Medical SchoolLondonUK

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