Transport of Nonelectrolytes
Depending on their size, degree of hydrophobicity and specific structural features, molecules can cross biological membranes by three principally distinct mechanisms: (1) Nonspecific “diffusion” through the lipid and, in a limited degree, through the polar parts of the membrane; (2) specific “carrier” transport—this category includes, as a subgroup, systems where the transported substance is altered chemically; (3) mechanisms involving profound, even if transient, changes in membrane architecture, such as pinocytosis, penetration of biopolymers.
KeywordsSimple Diffusion Accumulation Ratio Unstirred Layer Unidirectional Flux Trans Side
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