Biomembranes pp 289-302 | Cite as

Round Table Discussion Groups

  • Robert L. Post
  • Eric Holtzman
  • David C. White
  • Daniel Billen
  • Herbert A. Blough


The round-table group on (Na+ + K+)-ATPase discussed topics including the following:
  1. 1.

    Loss of dependence on K+ in the gills of euryhaline fish after adaptation of the fish from salt water to fresh water. Is there a replacement of one enzyme by another or controlled alteration of a single enzyme? Are there many varieties of Na+-dependent ATPase in general? Is there hormonal control of (Na+ + K+)-ATPase, particularly via aldosterone?

  2. 2.

    Mutagenic variation in ouabain-binding affinity of cells in tissue culture.

  3. 3.

    Variation in characteristics of erythrocyte (Na+ + K+)-ATPase in genetically related varieties of sheep with a high or low concentration of K+ in their red cells.

  4. 4.

    The relationship of (Na+ + K+)-ATPase to the transport of Na+ across epithelial tissue.

  5. 5.

    The mechanism of the therapeutic action of cardioactive steroids in the relief of congestive heart disease according to the hypothesis of Baker, Blaustein, Hidgkin and Steinhardt.

  6. 6.

    Purification of (Na+ + K+)-ATPase. Is there one or more than one peptide chain in the enzyme?

  7. 7.

    The reaction sequence of phosphorylation and dephosphonylation of this enzyme and remarkable effects of ethanol on the kinetics. Is there adequate evidence that so-called E1-P is necessarily a precursor of so-called E2-P?



Trans Fatty Acid Sialic Acid Residue Polyoma Virus Round Table Discussion Euryhaline Fish 
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Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • Robert L. Post
    • 1
  • Eric Holtzman
    • 2
  • David C. White
    • 3
  • Daniel Billen
    • 4
  • Herbert A. Blough
    • 5
  1. 1.Vanderbilt UniversityNashvilleUSA
  2. 2.Columbia UniversityNew YorkUSA
  3. 3.University of KentuckyLexingtonUSA
  4. 4.University of FloridaGainesvilleUSA
  5. 5.Scheie Eye InstituteUniversity of PennsylvaniaPhiladelphiaUSA

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