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Biomembranes pp 271-282 | Cite as

Surface Changes and Growth of Virus Transformed Cells

  • Michael Stoker

Abstract

The idea that the abnormal social behaviour of cancer cells may be due to changes in their surfaces has stimulated research over a long period, but until recently it has been difficult to interpret the findings through lack of adequate comparability with appropriate normal cells. It is now possible however, to use cloned cell lines which can be rapidly and reliably transformed by various tumour viruses so that normal and transformed progeny from the same original parent cell can be compared under a variety of growth conditions.

Keywords

Wheat Germ Agglutinin Saturation Density Rous Sarcoma Virus Serum Growth Factor Time Lapse Cinematography 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Abercrombie, M and Heaysman, J.E.M. Exp. Cell Res. 6, 293 (1954)PubMedCrossRefGoogle Scholar
  2. Ambrose, E.J., Dudgeon, J.A., Easty, D.M. and Easty, G.C. Exp. Cell Res. 24, 220 (1961)PubMedCrossRefGoogle Scholar
  3. Aub, J.C., Tieslau, C. and Lankester, A. Proc. U.S. Nat. Acad. Sci. 50, 613 (1963)CrossRefGoogle Scholar
  4. Baranska, W., Koldovsky, P. and Koprowski, H Proc. U.S. Nat. Acad. Sci. 67, 193 (1970)CrossRefGoogle Scholar
  5. Buck, C.A., Glick, M.C. and Warren, L. Biochemistry 9, 4567 (1970)PubMedCrossRefGoogle Scholar
  6. Burger, M.M. and Goldberg, A.R. Proc. U.S. Nat. Acad. Sci. 57, 359 (1967)CrossRefGoogle Scholar
  7. Clarke, G.D., Stoker, M.G.P., Ludlow, A. and Thornton, M. Nature 227, 798 (1970)PubMedCrossRefGoogle Scholar
  8. Clarke, G.D. and Stoker, M.G.P. Ciba Fndtn. Symp. “Growth control in cell cultures” (1971) Eds. G.E.W. Wostenholme and Julie Knight (in Press)Google Scholar
  9. Cline, M. and Livingston, D.C. Nature 1971 (in Press)Google Scholar
  10. Cumar, F.A., Brady, R.O., Kolodny, E.H., McFarland, V.W. and Mora, P.T. Proc. U.S. Nat. Acad. Sci. 67, 757 (1970)CrossRefGoogle Scholar
  11. Dulbecco, R. Nature 227, 802 (1970)PubMedCrossRefGoogle Scholar
  12. Dulbecco, R. and Eckhart, W. Proc. U.S. Nat. Acad. Sci. 67, 1775 (1970)CrossRefGoogle Scholar
  13. Dulbecco, R. and Stoker, M.G.P. Proc. U.S. Nat. Acad. Sci. 66, 204 (1970)CrossRefGoogle Scholar
  14. Eckhart, W., Dulbecco, R. and Burger, M.M. Proc. U.S. Nat. Acad. Sci. 68, 283 (1971)CrossRefGoogle Scholar
  15. Forrester, J.A., Ambrose, E.J. and Stoker, M.G.P. Nature 201, 945 (1964)PubMedCrossRefGoogle Scholar
  16. Foster, D.O. and Pardee, A.B. J. Biol. Chem. 244, 2675 (1969)Google Scholar
  17. Habel, K. Proc. Soc. Exp. Biol. N.Y. 106, 722 (1961)Google Scholar
  18. Hakamori, S. and Murakami, W.T. Proc. U.S. Nat. Acad. Sci. 59, 254 (1968)CrossRefGoogle Scholar
  19. Hgyry, P. and Defendi, V. Virology 41, 22 (1970)CrossRefGoogle Scholar
  20. Holley, R.W. and Kiernan, J.A. Proc. U.S. Nat. Acad. Sci. 60, 300 (1968)CrossRefGoogle Scholar
  21. Inbar, M. and Sachs, L. Proc. U.S. Nat. Acad. Sci. 63, 1418 (1969)CrossRefGoogle Scholar
  22. Macpherson, I. and Montagnier, L. Virology 23, 291 (1964)PubMedCrossRefGoogle Scholar
  23. Macpherson, I. and Stoker, M. Virology 16, 147 (1962)PubMedCrossRefGoogle Scholar
  24. Martin, G.S. Nature 227, 1021 (1970)PubMedCrossRefGoogle Scholar
  25. Mora, P.T., Brady, R.O., Bradley, R.M. and McFarland, V.W. Proc. U.S. Nat. Acad. Sci. 63, 1290 (1969)CrossRefGoogle Scholar
  26. O’Neill, C.J. Cell Sci. 3, 405 (1968)Google Scholar
  27. Paul, J., Broadfoot, MM. and Walker, P. Int. J. Cancer 1, 207 (1966)CrossRefGoogle Scholar
  28. Pollack, R.E., Green, H. and Todaro, G.J. Proc. U.S. Nat. Acad. Sci. 60, 126 (1968)CrossRefGoogle Scholar
  29. Robbins, P.W. and Macpherson, HA. Proc. Roy. Soc. Lond. B 177, 49 (1971)CrossRefGoogle Scholar
  30. Sjogren, H.O., Hellstrom, I. and Klein, G. Cancer Res. 21, 329 (1961)Google Scholar
  31. Stoker, M., O’Neill, C., Berryman, S. and Waxman, V. Int. J. Cancer 3, 683 (1968)PubMedCrossRefGoogle Scholar
  32. Taylor-Papadimitriou, J. and Stoker, M. Int. J. Cancer (in Press)Google Scholar
  33. Temin, H. Nature 1971 (in Press)Google Scholar
  34. Todaro, G.J. and Green, H. J. Cell Biol. 17, 299 (1963)PubMedCrossRefGoogle Scholar
  35. Todaro, G.J., Lazar, G. and Green, H. J. Cell Comp. Physiol. 66, 325 (1965)CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1971

Authors and Affiliations

  • Michael Stoker
    • 1
  1. 1.Imperial Cancer Research FundLincoln’s Inn FieldsLondonUK

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