Advertisement

Immunopathology of the Nervous System

  • R. M. Morrell
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 73B)

Abstract

The assignment for this presentation is construed as providing a framework of fact and concept from which the current excitement and directions of research in modern neuroimmunopathology can be perceived. The presentation will be that of a general review with great selectivity exercised in the choice of topics, bearing in mind that comprehensiveness, although desirable, leads to generalizations which may not take into account the tremendous subspecialization which has occurred in all branches of clinical and experimental pathology. Just as the failure of the instructive theory of immunity came about from the analysis of immunity at the molecular level without simultaneously considering cell-cell interactions, so immunopathology of the nervous system is now moving toward the elaboration of molecular concepts, having begun and continuing with the investigation of difficult systemic and intracellular interactions. Immunopathology of the nervous system includes not only the intracranial contents and those of the spinal canal but also the autonomic and peripheral nervous systems and the neuromuscular apparatus.

Keywords

Multiple Sclerosis Amyotrophic Lateral Sclerosis Schwann Cell Multiple Sclerosis Patient Progressive Multifocal Leukoencephalopathy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Bartfeld, H., Atoynatan, T., Int. Arch. Allergy Appl. Immunol., 39 (1970) 361.PubMedCrossRefGoogle Scholar
  2. 2.
    Bartfeld, H., Atoynatan, T., Brit. Med. J., 2 (1970) 91.PubMedCrossRefGoogle Scholar
  3. 3.
    Behan, P.O., Behan, W.M.H., Feldman, R.G. and Kies, M.W., Arch. Neurol., 27 (1972) 145.PubMedCrossRefGoogle Scholar
  4. 4.
    Bertrams, J., Kuwert, E., Liedtke, U., Tissue Antigens, 2 (1972) 405.PubMedCrossRefGoogle Scholar
  5. 5.
    Brockman, J.A., Stiffey, A.V., Experientia, 26 (1970) 413.PubMedCrossRefGoogle Scholar
  6. 6.
    Caspary, E.A., Field, E.J., Eur. Neurol., 4 (1970) 257.PubMedCrossRefGoogle Scholar
  7. 7.
    Caspary, E.A., Field, E.J., Brit. Med. J., 2 (1971) 613.PubMedCrossRefGoogle Scholar
  8. 8.
    Cendrowski, W., Neurol. Neurochir. Pol., 5 (1971) 133.PubMedGoogle Scholar
  9. 9.
    Cendrowski, W., Neurol. Neurochir. Pol., 4 (1970) 465.PubMedGoogle Scholar
  10. 10.
    Chuprikov, Á.P., Lab. Delo., 9 (1969) 551.PubMedGoogle Scholar
  11. 11.
    Ciongoli, Á.K., Lisak, R.P., Zeiman, B., Koprowski, H. and Waters, D., Neurology, 25 (1971) 891.CrossRefGoogle Scholar
  12. 12.
    Coates, A., Mackay, I.R., Crawford, J., Cell Immunol., 12 (1974) 370.PubMedCrossRefGoogle Scholar
  13. 13.
    Currie, S., Knowles, M., Brain, 94 (1971) 109.PubMedCrossRefGoogle Scholar
  14. 14.
    Dau, P.C., Peterson, R.D.A., Arch. Neurol., 23 (1970) 32.PubMedCrossRefGoogle Scholar
  15. 15.
    De Boer, W.G., Lancet, ii (1971) 96.CrossRefGoogle Scholar
  16. 16.
    Doherty, P.C., Zinkernagel, R.M., Transplant. Rev., 19 (1974) 89.PubMedGoogle Scholar
  17. 17.
    Field, E.J., Caspary, E.A., and Carnegie, P.R., Nature, 233 (1971) 284.PubMedCrossRefGoogle Scholar
  18. 18.
    Finkelstein, S., Walford, R.L., Myers, L.W. and Ellison, G.W., Lancet, i (1974) 736.CrossRefGoogle Scholar
  19. 19.
    Gallily, R., Ben-Ishay, Z., J.R.E.S., 18 (1975) 44.Google Scholar
  20. 20.
    Gregory, M.C., Hughes, J.T., J. Neurol., Neurosurg., Psychiat., 36 (1973) 769.CrossRefGoogle Scholar
  21. 21.
    Greisman, S.E., Hornick, R.B., J. Infect. Dis., 128 (1973) s265PubMedCrossRefGoogle Scholar
  22. 22.
    Hart, M.N., Hanks, D.T., and Mackay, R., Arch. Path., 93 (1972) 552.PubMedGoogle Scholar
  23. 23.
    Herndon, R.M., Griffin, D.E., McCormick, U. and Weiner, L. P., Arch. Neurol., 32 (1975) 32.PubMedCrossRefGoogle Scholar
  24. 24.
    Iwasaki, Y., McMichael, J. and Koprowski, H., Acta Neuropath., 31 (1975) 315.PubMedCrossRefGoogle Scholar
  25. 25.
    Jabbour, J.T., Roane, J.A., Sever, J.L., Neurology, 19 (1969) 929.PubMedCrossRefGoogle Scholar
  26. 26.
    Jersild, C., Fog, T., Hansen, G.S. and Ammitzbøll, T., Tissue Antigens, 3 (1973) 243.PubMedCrossRefGoogle Scholar
  27. 27.
    Jersild, C., Svejgaard, A., Fog, T. and Ammitzbøll, T., Tissue Antigens, 3 (1973) 243.PubMedCrossRefGoogle Scholar
  28. 28.
    Johnson, R.T., Gibbs, C.J., Arch. Neurol., 30 (1974) 36.PubMedCrossRefGoogle Scholar
  29. 29.
    Johnson, R.T., Herndon, R.M., In: Progress in Medical Virology, (Ed. J.L. Melnick) S. Karger, Basel, Switzerland (1974) 214.Google Scholar
  30. 30.
    Lamoreux, G., Carnegie, P.R., McPherson, T.A., Mackay, I.R. and Bernard, C., Ann. Inst. Pasteur, 118 (1970) 562.Google Scholar
  31. 31.
    Lampert, F., Lampert, P., Arch. Neurol., 32 (1975) 425.PubMedCrossRefGoogle Scholar
  32. 32.
    Lambert, C.D., Trewby, P.N., J. Neurol., Neurosurg., Psychiat., 37 (1974) 835.CrossRefGoogle Scholar
  33. 33.
    McDevitt, H.O., Bodner, W.F., Lancet, ii (1974) 1269.CrossRefGoogle Scholar
  34. 34.
    Mims, C.A., In: Progress in Medical Virology, (Ed. J.L. Melnick) S. Karger, Basel, Switzerland, (1974) 1.Google Scholar
  35. 35.
    Nathanson, N., Cole, G.A., Adv. Virus Res., 16 (1971) 397.CrossRefGoogle Scholar
  36. 36.
    Ogata, J., Feigin, I., Neurology, 25 (1975) 713.PubMedCrossRefGoogle Scholar
  37. 37.
    Payne, C.M., Sibley, W.A., Acta Neuropath., 31 (1975) 353.PubMedCrossRefGoogle Scholar
  38. 38.
    Poirier, J., Goutieres, F., Ribadeau Dumas, J.L., La Nouvelle Presse Medicale, 1 (1972) 1513.PubMedGoogle Scholar
  39. 39.
    Prineas, J., Science, 178 (1972) 760.PubMedCrossRefGoogle Scholar
  40. 40.
    Sheremata, W., Colby, S., Karkhanis, Y. and Eylar, E.H., Can. J. Neurol. Sci., 2 (1975) 87.PubMedGoogle Scholar
  41. 41.
    Sheremata, W., Colby, S., Lusky, G. and Cosgrove, J.B.R., Neurology, 25 (1975) 833.PubMedCrossRefGoogle Scholar
  42. 42.
    Sheremata, W., Cosgrove, J.B.R., Eylar, E.H., Arch. Neurol., 30 (1974) 1.CrossRefGoogle Scholar
  43. 43.
    Simon, J. and Anzil, A.P., Acta Neuropath., 27 (1974) 1.CrossRefGoogle Scholar
  44. 44.
    Stenwig, A.E., J. Neuropath., Exp. Neurol., 31 (1972) 696.Google Scholar
  45. 45.
    Tabira, T., Webster, H. F. and Wray, S.H., Arch. Neurol., 32 (1975) 1.CrossRefGoogle Scholar
  46. 46.
    Tanaka, R., Iwasaki, Y. and Koprowski, H., Arch. Neurol., 32 (1975) 80.PubMedCrossRefGoogle Scholar
  47. 47.
    Vuia, O., Internat. Res. Commun. Sys., (1973).Google Scholar
  48. 48.
    Wattre, P., Path.-Biol., 20 (1972) 793.Google Scholar
  49. 49.
    Webb, C., Teitelbaum, D., Abramsky, O., Lancet, ii (1974) 66.CrossRefGoogle Scholar
  50. 50.
    Weiner, L.P., Narayan, O., Progress in Medical Virology, S. Karger, Basel, Switzerland, 18 (1974) 229.Google Scholar
  51. 51.
    Westall, F.C., Immunochem., 11 (1974) 513.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • R. M. Morrell
    • 1
  1. 1.Baylor College of MedicineHoustonUSA

Personalised recommendations