Genetic Control of Bacterial Purine Phosphoribosyltransferases and an Approach to Gene Enrichment
Enteric bacteria such as Escherichia coli and Salmonella typhimurium possess three separate genes that control three different phosphoribosyltransferases (PRI). A-PRT (apt gene) is active only for adenine; G-PRT (gpt gene) converts guanine, hypoxanthine and xanthine; and H-PRT (hpt gene) is primarily active for hypoxanthine, poorly for guanine and not at all for xanthine.
KeywordsElution Pattern Cesium Chloride Strain TM445 Cellulose Column Chromatography Cesium Chloride Density Gradient
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