Skip to main content

Genetic Control of Bacterial Purine Phosphoribosyltransferases and an Approach to Gene Enrichment

  • Chapter

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 41A))

Abstract

Enteric bacteria such as Escherichia coli and Salmonella typhimurium possess three separate genes that control three different phosphoribosyltransferases (PRI). A-PRT (apt gene) is active only for adenine; G-PRT (gpt gene) converts guanine, hypoxanthine and xanthine; and H-PRT (hpt gene) is primarily active for hypoxanthine, poorly for guanine and not at all for xanthine.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Kalle, G. P. and Gots, J. S. Science, 142: 680 (1963).

    Article  CAS  Google Scholar 

  2. Gots, J. S., Benson, C. E., and Shumas, S. R. J. Bacteriol., 112: 910 (1972).

    PubMed  CAS  Google Scholar 

  3. Chou, J. Y. and Martin, R. G. J. Bacteriol., 112: 1010 (1972).

    PubMed  CAS  Google Scholar 

  4. Krenitsky, T. A., Neil, S. M., and Miller, R. L. J. Biol. Chem., 245: 2605 (1970).

    CAS  Google Scholar 

  5. Jessop, A. P. Mol. Genl. Genet., 114: 214 (1972).

    Article  CAS  Google Scholar 

  6. Roth, J. R. and Hoppe, I. Genetics, 71: 53 (1972).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1974 Plenum Press, New York

About this chapter

Cite this chapter

Gots, J.S., Benson, C.E. (1974). Genetic Control of Bacterial Purine Phosphoribosyltransferases and an Approach to Gene Enrichment. In: Sperling, O., De Vries, A., Wyngaarden, J.B. (eds) Purine Metabolism in Man. Advances in Experimental Medicine and Biology, vol 41A. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3294-7_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-3294-7_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3296-1

  • Online ISBN: 978-1-4684-3294-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics