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Enzymes of Purine Metabolism in Platelets: Phosphoribosylpyrophosphate Synthetase and Purine Phosphoribosyltransferases

  • Z. Jerushalmy
  • O. Sperling
  • J. Pinkhas
  • M. Krynska
  • A. de Vries
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 41A)

Abstract

Human platelets do not synthesize nucleotides de novo (1) but have been demonstrated to possess salvage pathways utilizing adenine and adenosine (2,3). On the other hand, no evidence has been reported as yet for the presence of hypoxanthine-guanine phosphoribosyltransfe-rase (HGPRT) in human platelets.

Keywords

Human Platelet Purine Nucleoside Purine Metabolism Purine Base Platelet Lysate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1974

Authors and Affiliations

  • Z. Jerushalmy
    • 1
  • O. Sperling
    • 1
  • J. Pinkhas
    • 1
  • M. Krynska
    • 1
  • A. de Vries
    • 1
  1. 1.Rogoff-Wellcome Medical Research Institute and the Metabolic Unit of Department of Medicine DTel-Aviv University Medical School, Beilinson HospitalPetah TikvaIsrael

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