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Monitoring of Cerebral Oxygenation in the Intensive Care Nursery

  • Jane E. Brazy
  • D. V. Lewis
  • M. H. Mitnick
  • F. F. Jöbsis-Vander Vliet
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 191)

Abstract

Prime objectives in neonatal intensive care include prevention of brain injury and maintanance of normal neurologic function. Since brain function is dependent upon adequate oxygen delivery, various techniques for oxygen monitoring have become integral parts of neonatal intensive care. However, most monitoring techniques currently in use determine oxygenation at sites distant from the brain (i.e. aorta, skin) and do not directly assess either cerebral oxygen delivery or oxygen utilization by the brain. Thus, an instrument which can provide continuous information on hemoglobin oxygenation and on cerebral oxidative metabolism may have marked advantages over current monitoring capabilities and offer the opportunity to observe the specific effects of medical therapies and nursing care on the infant’s cerebral oxygenation.

Keywords

Cerebral Oxygenation Hemoglobin Oxygenation Relative Blood Volume Impaired Autoregulation Cerebral Oxygen Delivery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    H. C. Lou, N. A. Lassen, and B. Friis-Hansen, Impaired autoregulation of cerebral blood flow in the distressed newborn infant. J. Pediatr. 94:118 (1979).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Jane E. Brazy
    • 1
  • D. V. Lewis
  • M. H. Mitnick
    • 1
  • F. F. Jöbsis-Vander Vliet
    • 1
  1. 1.Departments of Pediatrics and PhysiologyDuke University Medical CenterDurhamUSA

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