Abstract
Transport of oxygen to alveoli through the airway tree and to tissues through the vascular arborization both involve convection in large vessels followed by diffusion to the final 02 sink. At the transition between convection and diffusion, there is a steep drop of 02 concentration in the flowing medium. Gas in airways differs from the blood in that flow is bidirectional. We use a relatively simple computer model to demonstrate behavior of the steep drop when flow changes direction at end-inspiration.
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References
Baker, L. G., Ultman, J. S., and Rhoades, R. A., 1974, Simultaneous gas flow and diffusion in a symmetric airway system: a mathematical model, Respir, Physiol., 21:119.
Cumming, G., Crank, J., Horsfield, K., and Parker, I., 1966, Gaseous diffusion in the airways of the human lung, Respir. Physiol., 1:58.
Cumming, G., Horsfield, K., and Preston, S. B., 1971, Diffusion equilibrium in the lungs examined by nodal analysis, Respir, Physiol., 12:329.
Engel, L. A., Paiva, M., Siegler, D. I. M., and Fukuchi, Y., 1979, Dual tracer single breath studies of gas transport in the lung, Respir. Physiol., 36:103.
Engel, L. A., Wood, L. D. H., Utz, G., and Macklem, P. T., 1973, Gas mixing during inspiration, J. Appl. Physiol., 35:18.
LaForce, R. C., and Lewis, B. M., 1970, Diffusional transport in the human lung, J. APPl. Physiol., 28:291.
Okubo, T., and Piiper, J., 1974, Intrapulmonary gas mixing in excised dog lung lobes studied by simultaneous wash-out of two inert gases, Respir. Physiol., 21:223.
Pack, A., Hooper, M. B., Nixon, W., and Taylor J. C., 1977, A computational model of pulmonary gas transport incorporating effective diffusion, Respir. Physiol., 29:101.
Paiva, M., 1973, Gas transport in the human lung, J. Appl. Physiol., 35:401.
Paiva, M., Lacquet, L. M., and van der Linden, L. P., 1976, Gas transport in a model derived from Hansen-Ampaya anatomical data of the human lung, J. Adpl. Physiol., 41:115.
Scherer, P. W., Shendalman, L. H., and Greene, N. M., 1972, Simultaneous diffusion and convection in single breath lung washout, Bull. Math. Biophys., 34:393.
Sikand, R. S., Magnussen, H., Scheid, P., and Piiper, J., 1976, Convective and diffusive gas mixing in human lungs: experiments and model analysis, J. Appl. Physiol., 40:362.
Van Liew, H. D., Thalmann, E. D., and Sponholtz, D. K., 1981, Hindrance to diffusive gas mixing in the lung in hyperbaric environments, J. Appl. Physiol., 51:243.
Weibel, E. R., 1963, “Morphometry of the Human Lung,” Springer-Verlag, Berlin.
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© 1985 Plenum Press, New York
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Van Liew, H.D., Murray, K.R. (1985). Convection/Diffusion Interactions in Oxygen Transport: Effect of Flow Reversal in Lung Airways. In: Kreuzer, F., Cain, S.M., Turek, Z., Goldstick, T.K. (eds) Oxygen Transport to Tissue VII. Advances in Experimental Medicine and Biology, vol 191. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3291-6_61
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DOI: https://doi.org/10.1007/978-1-4684-3291-6_61
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-3293-0
Online ISBN: 978-1-4684-3291-6
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