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Red Cell O2 Transport at Altitude and Altitude Training

  • Heimo Mairbäurl
  • Wolfgang Schobersberger
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 191)

Abstract

Ascent to altitude brings people, who are adapted to low elevations, into a more or less hypoxic environment. The degree of hypoxia depends on the altitude. It has to be distinguished between moderate altitude, which we understand to be between 1600 m and 3500 m above sea level, and high altitude, which are elevations higher than 3500 m. This distinction is necessary from a physiological point of view, since different mechanisms are involved in the adaptation of oxygen transport by the erythrocyte to moderate altitude or high altitude.

Keywords

Exercise Performance Hill Coefficient Oxygen Affinity Prolonged Stay Training Subject 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1).
    ALEXANDER, J.K., L.H. HARTLEY, M. MODELSKI and R.F. GROVER (1967). Reduction of stroke volume during exercise in man following ascent to 3100 m altitude. J.Appl.Physiol. 23:849–858.PubMedGoogle Scholar
  2. 2).
    BAUER, C. and A.M. RATHSCHLAG-SCHÄFER (1968). The influence of alr-dosterone and Cortisol on oxygen affinity and cation concentration of the blood. Respir.Physiol. 5:360–370.PubMedCrossRefGoogle Scholar
  3. 3).
    CUNNINGHAM, D.A. and J.R. MAGEL (1970). The effect of moderate altitude on post-exercise lactate. Int.Z.angew.Physiol. 29:94–100.PubMedGoogle Scholar
  4. 4).
    DØLL, E., J. KEUL and C. MAIWALD (1968). Oxygen tension and acid base equilibria in venous blood of working muscle. Am.J.Physiol. 215:23–29.PubMedGoogle Scholar
  5. 5).
    EATON, J., T.D. SELTON and E. BERGER (1974). Survival at extreme altitude: Protective effect of increased hemoglobin-oxygen affinity. Science 183:743–744.PubMedCrossRefGoogle Scholar
  6. 6).
    FORNAINI, G., M.MAGNANI, M.DACHA and V.STICCHI (1978). Relationship between glucose phosphorylating activities and erythrocyte age. Mech.Aging Develop. 8:249–256.CrossRefGoogle Scholar
  7. 7).
    HUMPELER, E., K. INAMA and P. DEETJEN (1979). Improvement of tissue oxygenation during a 20 day’s stay at moderate altitude in Connection with mild exercise. Klin.Wschr. 57:267–272.PubMedCrossRefGoogle Scholar
  8. 8).
    HUMPELER, E., K. INAMA and H. JUNGMANN (1980). Die Sauerstoffaffinität des Hämoglobins 3 Stunden nach passivem Höhenwechsel von 400 auf 1800 m. Wiener Klin.Wschr. 92:326–332.Google Scholar
  9. 9).
    HUMPELER, E., F. SKRABAL and G. BARTSCH (1980). Influence of exposure to moderate altitude on plasma concentrations of Cortisol, aldosterone, renin, testosterone and gonadotropins. Eur.J.Appl.Physiol. 45:167–176.CrossRefGoogle Scholar
  10. 10).
    HURTADO, A., C.F. MERINO and D. DEGADO (1945). Influence of anoxemia on the hematopoetic activity. Arch.Intern.Med. 75:284–323.CrossRefGoogle Scholar
  11. 11).
    LENFANT, C., J.D.TORRANCE, R.WOODSON and C.A. FINCH (1970). Adaptation to hypoxia. In: Red Cell Metabolism and Function, G.BREwer, ed. p. 203–212. New York, Plenum Press.CrossRefGoogle Scholar
  12. 12).
    MAIRBÄURL, H., and E. HUMPELER (1981). In vitro influences of adrenaline on erythrocyte metabolism and on oxygen affinity of hemoglobin. In: The Red Cell: Fifth Ann Arbor Conference, G. Brewer, ed. p.311–319. New York, A.R. Liss.Google Scholar
  13. 13).
    RAPOPORT, I., T.A. RAPOPORT and S.M. RAPOPORT (1978). Analysis of pH-induced changes of glycolysis of human erythrocytes. Acta Biol.Med.Germ. 37:393–401.PubMedGoogle Scholar
  14. 14).
    RÖRTH, M., F. NYGAARD and H.H. PARVING (1972). Effect of exposure to simulated high altitude on human red cell phosphates and oxygen affinity of Hb. Influence of exercise. Scand.J.clin.Lab.Invest. 29:329–333.PubMedCrossRefGoogle Scholar
  15. 15).
    TURKMENOW, M.T. and J.J. IMANKULOV (1975). Human work capacity at high altitude. Xogm.Biol.Aviakosm.Med. 9:70.Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Heimo Mairbäurl
    • 1
  • Wolfgang Schobersberger
    • 1
  1. 1.Department of PhysiologyUniversity of InnsbruckInnsbruckAustria

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