Oxygen Binding Properties of Early Definitive Red Cells from Normoxic and Hypoxic Chick Embryos
During vertebrate ontogeny one observes large changes of the oxygen binding properties of the blood, reflecting the transition from the specific embryonic hemoglobins to fetal and/or adult hemoglobin as well as changes in the concentration of those metabolites of the red cell that act as allosteric regulators of hemoglobin function. While these changes have been extensively investigated for later stages of development in mammals and birds, there exist only few data on the functional properties of embryonic blood (1,2,3), and control of hemoglobin function at this stage is not well understood.
KeywordsOxygen Affinity Oxygen Binding Adult Hemoglobin Embryonic Blood Oxygen Binding Property
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