Advertisement

Oxygen Binding Properties of Early Definitive Red Cells from Normoxic and Hypoxic Chick Embryos

  • Rosemarie Baumann
  • Jens Fischer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 191)

Abstract

During vertebrate ontogeny one observes large changes of the oxygen binding properties of the blood, reflecting the transition from the specific embryonic hemoglobins to fetal and/or adult hemoglobin as well as changes in the concentration of those metabolites of the red cell that act as allosteric regulators of hemoglobin function. While these changes have been extensively investigated for later stages of development in mammals and birds, there exist only few data on the functional properties of embryonic blood (1,2,3), and control of hemoglobin function at this stage is not well understood.

Keywords

Oxygen Affinity Oxygen Binding Adult Hemoglobin Embryonic Blood Oxygen Binding Property 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    J.G. Gilman. Rat embryonic and fetal erythrocytes.High 2,3 — bisphosphoglycerate and low oxygen affinity in vitro for nucleated embryonic red cells.Biochem. J. 192: 335, 1980Google Scholar
  2. 2.
    R. Baumann, S.Padeken and E.A. Malier. Functional properties of embryonic chicken hemoglobins. J. Appl. Physiol. 53: 1439, 1982PubMedGoogle Scholar
  3. 3.
    G.N. Lapennas and R. B. Reeves. Oxygen affinity and equilibrium curve shape in blood of chicken embryos. Respir. Physiol. 52: 13, 1983PubMedCrossRefGoogle Scholar
  4. 4.
    G.A. Bruns and V.M. Ingram. The erythroid cells and hemoglobins of the chick embryo. Philos. Trans. R. Soc. London Scr. B. 266: 225, 1973CrossRefGoogle Scholar
  5. 5.
    L. Lemez. Quantitative Studie der fünf Typen der definitiven Erythrozyten (E II) beim Hühnerembryo.Verh. Anat. Ges. 71: 235, 1977PubMedGoogle Scholar
  6. 6.
    R. Baumann, S. Padeken, E.A. Haller and Th. Brilmayer. Effect of hypoxia on oxygen affinity , hemoglobin pattern and blood volume of early chicken embryos. Am. J. Physiol. 244: R 733, 1983Google Scholar
  7. 7.
    L. Cirotto, A. Scotto di Telia and G. Geraci. The hemoglobin of the developing chicken embryos.Fractionation and globin composition of the individual component of total erythrocytes and a single erythrocyte type. Cell Differ. 4: 87, 1975PubMedCrossRefGoogle Scholar
  8. 3.
    B.S. Chapman and A. J. Tobin. Distribution of developmentally regulated hemoglobin in embryonic erythroid populations .Dev.Biol. 69: 375, 1979Google Scholar
  9. 9.
    G.R. Bartlett and T.A. Borgese. Phosphate compounds in red cells of the chicken and duck embryo and hatchling.Comp. Biochem.Physiol. A. 55: 207, 1976Google Scholar
  10. 10.
    H. Tazawa , T. Ono and M. Mochizuki.Oxygen dissociation curve for chorioallantoic blood for chicken embryo.J.Appl. Physiol. 40:393 1976PubMedGoogle Scholar
  11. 11.
    A.L. Romanoff.” Biochemistry of the avian embryo.A quantitative analysis of prenatal development”, Interscience, New York, 1969Google Scholar
  12. 12.
    R. Baumann. Regulation of oxygen affinity of embryonic chicken blood during hypoxia. In press.Google Scholar
  13. 13.
    R. Baumann and G. Gros.A comparative study of the aggregation of avian embryonic and adult hemoglobin.in: “ Hemoglobin “. A.G. Schnek and C. Paul eds. Editions de l’Université de Bruxelles, Brussels, 1984CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Rosemarie Baumann
    • 1
  • Jens Fischer
    • 1
  1. 1.Zentrum Physiologie Medizinische HochschuleHannoverGermany

Personalised recommendations