Gas Exchange during Peritoneal Perfusion with Perfluorocarbon Emulsions
The fact that fluorocarbons have a very high solubility for oxygen was very dramatically demonstrated by Clark and Gollan (1966), when they were able to show survival of mice completely immersed in these liquids for extended periods of time. The animals were able to obtain sufficient oxygen by respiring the liquid. After removal from the fluorocarbons the animals showed no apparent ill effects from the experience.
KeywordsPancuronium Bromide Blood Substitute Arterial Carbon Dioxide Tension Paraquat Poisoning Perfluorocarbon Emulsion
Unable to display preview. Download preview PDF.
- Awad, J.A., Brassard, A., Caron, W.M. and Cadrin, C., 1970b. Intraperitoneal oxygenation with hydrogen peroxide. Int. Surg. 54:276Google Scholar
- Geyer, R. P., 1975. Review of perfluorochemical-type blood substitutes. Proc. Xth Intern Cong Nutrition Symposium on PFC Artificial Blood, Kyoto, Japan: p.3.Google Scholar
- Grote, J., Steuer, K., Müller, R., Söntgerath, C., and Zimmer, K., 1984, O2 and CO2 transport properties of fluorocarbon emulsions (Fluosol-DA) and Blood-Fluosol-DA mixtures. Abstracts of the Intern. Soc. on Oxygen Tranport to Tissue, Nijmegen, The Netherlands : p 38.Google Scholar
- Naito R. and Yokoyama K., 1978. In: Perfluorochemical blood substitutes. Green Cross Corporation Technical Information Service No.5, Osaka, Japan.Google Scholar