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Skeletal Muscle Capillarity in Hyperthyroid and Hypothyroid Rats

  • A. H. Sillau
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 191)

Abstract

The capacity of the oxygen transport system to deliver O2 to the muscle fibers depends, among other things, on the density and the geometric arrangement of the capillary network. Romanul (1965) and Myraghe (1978) have shown that the number of capillaries around the skeletal muscle fibers is directly correlated with the oxidative capacity of the fibers. On the other hand, Maxwell et al. (1980) and Zumstein et al. (1983) have presented evidence that runs counter to the above. Maxwell et al. (1980) studied different muscles from different animal species and muscle to muscle and species to species variability could have obscured the relationship between capillarity and oxidative capacity. In addition, both Maxwell et al. (1980) and Zumstein et al. (1983) reported their values of capillarity as capillary density and capillary to fiber ratio without taking into consideration the effect that fiber cross sectional area has on these parameters. It has been shown that this may lead to erroneous interpretations of the experimental results (Ripoll et al., 1979).

Keywords

Diffusion Distance Oxidative Capacity Capillary Density Puerto Rico 00936 Fiber Cross Sectional Area 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • A. H. Sillau
    • 1
  1. 1.Department of Physiology and Biophysics School of MedicineUniversity of Puerto RicoSan JuanPuerto Rico

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