Myocardial Ischemic Injury and β-Adrenergic Receptors in Perfused Working Rabbit Hearts
Adrenergic nerve system modulates a host of diverse physiological functions in health and diseases.1–4 Recent advances in the study of adrenergic receptors have contributed greatly to an understanding of both alpha- and beta-adrenergic receptors and their subtypes. Availability of radioactive agonists and antagonists in high specific activity allowed to access directly the density and property of the receptors. However, their role in acute effect of myocardial ischemia on cardiac metabolism and function is poorly understood.
KeywordsIschemic Heart Adrenergic Receptor Contractile Force Left Ventricular Pressure Rabbit Heart
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