Myocardial Capillarity of Rats Exposed to Simulated High Altitude
The main purpose of the present study was to apply our new method of computerized evaluation of “capillary domains” to practical problems dealing with capillarization of hearts from rats adapted to high altitude. The method itself is described in detail in another contribution to this volume (Hoofd et al., 1985). It is a convenient way to obtain not only the average radius of the Krogh tissue cylinder but also the degree of heterogeneity in capillary spacing. Both of these parameters are important determinants of tissue oxygenation. The former is included in the Krogh-Erlang equation while the latter has been only recently reported as a factor influencing tissue oxygen supply (Turek and Rakusan, 1981).
KeywordsLeft Ventricle Left Ventricular Myocardium Simulated Altitude Ventricular Weight Tissue Cylinder
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