In Situ NADH Laser Fluorimetry and Its Application to the Study of Cardiac Metabolism
The in vivo fluorimetry of NADH has proven to be a very efficient method for non-destructive investigation of organ metabolism. First defined by Chance and his group(1) this method u/as subsequently extended to numerous experimental models and provided important information on challenging topics, such as the importance of the border zone in myocardial infarction.
KeywordsCardiac Metabolism Organ Metabolism Reference Light Ischemia Test Anoxia Period
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- 1.B. Chance, J.R. Williamson, D. Jamieson, and B. Schroener, Properties and kinetics of reduced pyridine nucleotide fluorescence of the isolated and in vivo rat heart, Biochem.Z. 341: 357–377 (1965).Google Scholar