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Oxygen Supply to Hypothermic Isolated Working Heart During Blood Acid-Base Changes

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Oxygen Transport to Tissue VII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 191))

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Abstract

Alterations of thermal state induce changes in oxygen transport as a consequence of shifting metabolic demand, modifications of acid-base parameters and changes in blood oxygen affinity. It is now recognized that, when temperature is modified, variation in pH of biological fluids parallels modifications in the neutral point of water which is temperature dependent1,2. Therefore, pH adjustment, when organs from homeotherms are subjected to hypothermia as presently practiced in cardiac surgery or organ preservation, is justified.

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© 1985 Plenum Press, New York

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Sinet, M., Muffat-Joly, M., Henzel, D., Pocidalo, J.J. (1985). Oxygen Supply to Hypothermic Isolated Working Heart During Blood Acid-Base Changes. In: Kreuzer, F., Cain, S.M., Turek, Z., Goldstick, T.K. (eds) Oxygen Transport to Tissue VII. Advances in Experimental Medicine and Biology, vol 191. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-3291-6_22

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  • DOI: https://doi.org/10.1007/978-1-4684-3291-6_22

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-3293-0

  • Online ISBN: 978-1-4684-3291-6

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