Distribution of Mitochondria Relative to Capillaries in Guinea Pig Myocardium

  • Susan R. Kayar
  • N. Banchero
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 191)


The distribution of mitochondria relative to capillaries is important in respiratory physiology because it reflects the distribution of distances over which oxygen diffuses from its source in capillaries to its site of utilization in mitochondria. Mitochondrial distribution also reflects the distribution of distances over which high-energy phosphates must be transferred from their site of formation in the mitochondria to their site of utilization in the myofibrils. In this study, we devised a simple method for measuring mitochondrial distributions. This method was then used to measure the distribution of mitochondria relative to capillaries in the right ventricles of four guinea pigs of differing capillary densities.


Right Ventricle Volume Density Capillary Density Mitochondrial Distribution Cavia Porcellus 
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  1. Kayar, S.R., Archer, P.G., Lechner, A.J., and Banchero, N., 1982, The closest individual method in the analysis of the distribution of capillaries, Microvasc. Res., 24:326–341.PubMedCrossRefGoogle Scholar
  2. Kayar, S.R., and Banchero, N., 1983, Distribution of capillaries and diffusion distances in guinea pig myocardium, Pflugers Arch., 396:350–352.PubMedCrossRefGoogle Scholar
  3. Kayar, S.R., and Banchero, N., 1984, Myocardial capillarity in acclimation to hypoxia, Pflugers Arch., (in press).Google Scholar
  4. Mainwood, G.W., and Rakusan, K., 1982, A model for intracellular energy transport, Can. J. Physiol. Pharmacol., 60:98–102.PubMedCrossRefGoogle Scholar
  5. Meyer, R.A., Sweeney, H.L., and Kushmerick, M.J., 1984, A simple analysis of the “phosphocreatine shuttle”, Am. J. Physiol., 246;(Cell Physiol. 15);C365-C377.Google Scholar
  6. Weibel, E.R., 1979, “Stereological methods. Vol. 1. Practical methods for biological morphometry”, Academic Press, London, 97–112.Google Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Susan R. Kayar
    • 1
  • N. Banchero
    • 1
  1. 1.Department of PhysiologyUniversity of Colorado School of MedicineDenverUSA

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