Blood and Tissue Oxygenation during Hemorrhagic Shock as Determined with Ultramicro Oxygen Electrodes
Recent clinical and laboratory observations in the field of shock have centered attention upon deficits in pulmonary function as one of the major causes of death and morbidity following shock and trauma.1,2,3,4 Following the initial proposal that an oxygen debt was accumulated in hemorrhagic shock,5 other investigators have found that an oxygen deficit indeed did occur irk hemorrhagic shock and appeared to correlate with irreversibility.6,7 Evidence in the literature is scanty concerning direct measurements of tissue pO2 during hemorrhagic shock and is conflicting concerning arterial pO2 measurements in the same condition. The experiments reported here utilize an ultramicro oxygen electrode to determine arterial pO2 and renal and cerebral parenchymal pO2 during a standard episode of hemorrhagic shock.
KeywordsToxicity Lactate Heparin Defend Pentobarbital
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