Signs of Hypoxia in the Small Intestine of the Rat during Hemorrhagic Shock
The photometric measurement of fluorescence emitted by reduced pyridine nucleotides upon ultraviolet stimulation (1,3) and the polarographic measurement of PO2 (5) in tissues and organs have provided detailed information about the local effects of disturbances of O2 supply and of microcirculation. Under experimental conditions in which circulating blood is a factor it is also necessary to measure absorbancy changes of hemoglobin by reflectance photometry in order to accurately evaluate changes in reduced PN fluorescence (6,9,11). In the present study both the photometric and polarographic techniques have been focused on the small intestine of urethane anesthetized rats subjected to periodic, standardized hemorrhages.
KeywordsOxygen Transport Local Blood Flow Rhythmic Oscillation Compensatory Phenomenon Early Hemorrhage
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