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The Local Oxygen Supply in Tissue of Abdominal Viscera and of Skeletal Muscle in Extreme Hemodilution with Stromafree Hemoglobin Solution

  • L. Sunder-Plassmann
  • E. Sinagowitz
  • R. Rink
  • R. Dieterle
  • K. Mebmer
  • M. Kessler
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 37 A)

Abstract

Stromafree, non nephrotoxic hemoglobin solutions have become a subject of great interest in recent years, since in all cases where a rapid normalization of a disturbed oxygen transport to tissues is required, the theoretical advantages of hb-solution, as compared to whole blood or conventional plasma substitutes are obvious: Unlimited supply and storage, no risk of serum hepatitis, chemical O2binding, and low viscosity. To evaluate its effectiveness in vivo the changes in tissue PO2 of various organs have been investigated in extreme hemodilution with hb-solution.

Keywords

Blood Viscosity Abdominal Viscus Hemoglobin Solution Unlimited Supply Plasma Hemoglobin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    KESSLER, M., GRUNEWALD, W. Progr.Resp.Res. 3: 147–152 ( Karger, Basel/New York 1969 ).Google Scholar
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    MESSMER, K., LEWIS, H.D., SUNDER-PLASSMANN, L., KLÖVEKORN, W.P.,MENDLER, N. and HOLPER, K. Europ.Surg.Res. 4: 55 (1972).CrossRefGoogle Scholar
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    SUNDER-PLASSMANN, L.,JESCH, F.,GROHMANN, W.,SEIFERT, J. and MESSMER, K. Proc. 7th Conf. Microcirculation, Aberdeen (Karger Basel) in pressGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1973

Authors and Affiliations

  • L. Sunder-Plassmann
    • 1
    • 2
  • E. Sinagowitz
    • 1
    • 2
  • R. Rink
    • 1
    • 2
  • R. Dieterle
    • 1
    • 2
  • K. Mebmer
    • 1
    • 2
  • M. Kessler
    • 1
    • 2
  1. 1.Institut f. Surgical ResearchUniversity MunichGermany
  2. 2.Apllied PhysiologyMax-Planck-Inst.DortmundW.Germany

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