A New Long-Term Method for the Measurement of NADH Fluorescence in Intact Rat Brain with Chronically Implanted Cannula

  • A. Mayevsky
  • B. Chance
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 37 A)


The method developed by Chance et al. (1) which measures the oxidation-reduction state of NADH in vivo by surface fluorometry is in use in many laboratories. In all cases, acute preparations are used.


Nitrogen Cycle Spreading Depression Pyridine Nucleotide NADH Oxidation Fluorescence Trace 
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Copyright information

© Springer Science+Business Media New York 1973

Authors and Affiliations

  • A. Mayevsky
    • 1
  • B. Chance
    • 1
  1. 1.Johnson Research Foundation, School of MedicineUniversity of PennsylvaniaPhiladelphiaUSA

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