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2,3-DPG-Induced Displacements of the Oxyhemoglobin Dissociation Curve of Blood: Mechanisms and Consequences

  • Jochen Duhm
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 37 A)

Abstract

In this paper an attempt will be made to analyze the effect of 2,3-diphosphoglycerate (DPG) on the oxygen affinity of intact human erythrocytes. Furthermore, the DPG-induced changes of oxygen release and Po2 in the tissues will be estimated quantitatively in a theoretical approach. Finally, an experimental procedure is proposed which might be suitable to elucidate experimentally the physiological importance of the DPG mechanism.

Keywords

Tissue Oxygenation Oxygen Transport Oxygen Affinity Purine Nucleoside Oxygen Release 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1973

Authors and Affiliations

  • Jochen Duhm
    • 1
  1. 1.Department of PhysiologyMedical Faculty Technical UniversityAachenGermany

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