The Influence of Allopurinol in Customary and in Slow Release Preparation on Different Parameters of Purine and Pyrimidine Metabolism
Allopurinol is widely used as a hypouricemic agent in man. This compound serves as both a substrate and an inhibitor of xanthine oxidase the enzyme which catalyses the oxidation of hypoxanthine to xanthine and xanthine to uric acid. Allopurinol itself is rapidly oxidized in vivo by xanthine oxidase to oxipurinol, which is also an inhibitor of xanthine oxidase,
KeywordsUric Acid Xanthine Oxidase Serum Uric Acid Renal Excretion Uric Acid Level
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