Influence of Urate on Connective Tissue Metabolism

  • H. W. Stuhlsatz
  • W. Enzensberger
  • H. Greiling
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 76B)


Monosodium urate deposits almost exclusively in the connective tissue of patients with gout. Thereby the question arises why the connective tissue is the predilective locus for monosodium urate. Several theories about the localised deposition of monosodium urate crystals in connective tissue demonstrate the interaction of urate with the components of the connective tissue.


Synovial Fluid Lysosomal Enzyme Monosodium Urate Sulfatase Activity Gouty Attack 


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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • H. W. Stuhlsatz
    • 1
  • W. Enzensberger
    • 1
  • H. Greiling
    • 1
  1. 1.Department of Clinical ChemistryTechnical University AachenGermany

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