Uptake of Hypoxanthine in Human Erythrocytes
The concentration of oxypurines in the plasma is known to be rather low (10 – 40 μM) (6). Since the formation of purines is accomplished to a great extent by the liver (7, 8), a transport of purines by erythrocytes from liver to tissues with limited or no capacity of de novo purine synthesis has been postulated (1, 3). For this function erythrocytes should possess the ability to perform a fast uptake and release of these purines operating selectively under different conditions.
KeywordsUric Acid Incubation Medium Human Erythrocyte Purine Metabolism Purine Synthesis
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