Control of Net Cellular Uptake of Adenosine from the Lumen Side of the Guinea Pig Jejunal Epithelium

  • N. Kolassa
  • R. Stengg
  • K. Turnheim
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 76B)


The mechanism of intestinal purine absorption is not well defined. The assumption that nucleotides are not able to permeate cell membranes renders nucleosides and nucleo-bases as the only chemical forms for the absorption of the purine moiety. While some although contraversial reports exist on the intestinal permeation of purine bases (Schanker et al., 1963; Oh et al., 1967; Berlin and Hawkins, 1968; Khan et al., 1975), no data are available concerning the absorptive mechanism of purine nucleosides. Therefore we investigated this problem focusing the main interest on the permeation process of adenosine.


Adenosine Deaminase Purine Nucleoside Lumen Side Blood Side Adenosine Uptake 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • N. Kolassa
    • 1
  • R. Stengg
    • 1
  • K. Turnheim
    • 1
  1. 1.Department of PharmacologyUniversity of ViennaViennaAustria

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