Factors Affecting Urate Reabsorption in the Rat Kidney

  • F. Lang
  • R. Greger
  • P. Deetjen
  • F. G. Knox
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 76B)


Urate handling in the rat kidney has been shown to involve bidirectional transport in the proximal tubule, net reabsorption in the loops of Henle and negligible transport in the distal nephron. In this paper, results will be discussed describing the effects of luminal urate concentration, pH and flow rate on urate reabsorption.


Uric Acid Proximal Tubule Urinary Flow Rate Urate Concentration Osmotic Diuresis 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • F. Lang
    • 1
    • 2
  • R. Greger
    • 1
    • 2
  • P. Deetjen
    • 1
    • 2
  • F. G. Knox
    • 1
    • 2
  1. 1.Institut of PhysiologyUniversity of InnsbruckInnsbruckAustria
  2. 2.Dept. of PhysiologyMayo Med. SchoolRochesterUSA

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