Effect of Phospholipid Liposomes on the Regulation of Cerebral Metabolism

  • G. Toffano
  • A. Leon
  • G. Savoini
  • P. Orlando
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 83)


In studying the pharmacological effects of a sonicated dispersion of bovine brain phospholipids on CNS, the following observations have been made: a) in animals, increase of both the conditioning avoidance response and motor activity (Toffano et al., 1976b) increase of brain glucose (Bruni et al., 1976a; 1976b) and of brain phospholipid synthesis (Orlando et al., 1976); and b) in men, decrease of prolactin secretion (Polleri et al., unpublished).


Tyrosine Hydroxylase Adenylate Cyclase Dopaminergic System Serum Prolactin Prolactin Secretion 
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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • G. Toffano
    • 1
  • A. Leon
    • 1
  • G. Savoini
    • 1
  • P. Orlando
    • 2
  1. 1.F.I.D.I.A. Res. Lab.Abano TermeItaly
  2. 2.Institute of PharmacologyUniversity S. CuoreRomeItaly

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