Studies on the Functions of Gangliosides in the Central Nervous System

  • R. Caputto
  • A. H. R. de Maccioni
  • B. L. Caputto
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 83)


No specific functions have been found for most of the great variety of complex lipids, including the gangliosides. These last compounds, at a concentration of 3 per thousand in gray matter are, in this part of the nervous tissue about twice as concentrated as in white matter and at least ten fold higher than in any other tissue of extra-neural origin.


Sialic Acid Carbohydrate Chain Chloroacetic Acid Subcellular Organelle Acid Soluble Fraction 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Caputto B. L., Maccioni A. H. R. & Caputto R. (1975) Nature 257, 492–493PubMedCrossRefGoogle Scholar
  2. Caputto R., Maccioni A. H. R. & Caputto B. L. (1976) Biochem. Biophys. Res. Commun. (In press)Google Scholar
  3. Dunn A., Brogan L., Entingh T., Gispen W. H., Machlus B., Perumal R. & Ress H. D. In F. O. Schmidt (Ed). The Neurosciences, Third Study Program, M.I.T. Press, Cambridge, Mass. 1973, pp. 679–684Google Scholar
  4. Eichberg J., Whittaker V. P. & Dawson R. M. C. (1964) Biochem. J. 92, 91–96PubMedGoogle Scholar
  5. Fenster L. J. & Copenhaver J. H. (1967) Biochim. Biophys. Acta 137, 406–408PubMedGoogle Scholar
  6. Igarashi M. & Suzuki K. (1976) J. Neurochem. 27, 859–866PubMedCrossRefGoogle Scholar
  7. Irwin L. N. & Samson F. E. (1971) J. Neurochem. 18, 203–211PubMedCrossRefGoogle Scholar
  8. Maccioni A. H. R., Gimenez M. S. & Caputto R. (1971) J. Neurochem. 18, 2362–2370CrossRefGoogle Scholar
  9. Maccioni A. H. R., Gimenez M. S., Caputto B. L. & Caputto R. (1974) Brain Research 73, 503–511PubMedCrossRefGoogle Scholar
  10. Maccioni H. J. F., Arce A., Landa C. & Caputto R. (1974) Biochem. J. 138, 291–298PubMedGoogle Scholar
  11. Stefanovic V., Ledig M. & Mandel P. (1976) J. Neurochem. 27, 799–805PubMedCrossRefGoogle Scholar
  12. Tanaka R. & Strickland K. P. (1965) Arch. Biochem. Biophys. 111, 583–592PubMedCrossRefGoogle Scholar
  13. Trams E. G. & Lauter C. G. (1974) Biochim. Biophys. Acta 345, 180–197PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • R. Caputto
    • 1
  • A. H. R. de Maccioni
    • 1
  • B. L. Caputto
    • 1
  1. 1.Departamento de Química BiológicaFacultad de Ciencias Químicas Universidad Nacional de CórdobaCórdobaArgentina

Personalised recommendations