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Interactions with Phospholipid Monolayers of Lipids and Water-Soluble Compounds That Induce Membrane Fusion

  • B. Maggio
  • J. A. Lucy
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 83)

Abstract

Hen erythrocytes fuse into multinucleated cells on incubation under defined conditions “in vitro” with a variety of chemical agents. These include various unsaturated and low-melting fat-solu ble substance (Ahkong et al., 1973; 1974), dimethyl sulphoxide, glycerol and other polyols, and poly(ethyleneglycol)(Ahkong et al., 1975a; 1975b). The present communication reports some effects of these compounds on phospholipid monolayers that may be related to the molecular mechanism of chemically-induced membrane fusion.

Keywords

Lipid Bilayer Surface Potential Membrane Fusion Dimethyl Sulphoxide Polar Head Group 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Plenum Press, New York 1977

Authors and Affiliations

  • B. Maggio
    • 2
  • J. A. Lucy
    • 1
  1. 1.Department of Biochemistry & Chemistry Royal Free Hospital School of MedicineUniversity of LondonLondonUK
  2. 2.Departamento de Química BiológicaFacultad de Ciencias QuímicasCórdobaArgentina

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