A Comparison of Transcutaneous and Arterial PO2 in Sick Neonates

  • Linda P. Soutter
  • Dawood Parker
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)


We have investigated the reliability of a transcutaneous PO2 sensor — the Hoffmann la Roche Oxygen Monitor 5300 — for the continuous assessment of the arterial PO2 of sick infants over periods of several hours. The PO2 transducer — developed by Eberhard and his colleagues — uses a large cathode 4 mm in diameter in conjunction with a membrane of low oxygen permeability to prevent alteration of the oxygen profile in the tissue by the oxygen consumption of the sensor. The transducer is heated to produce local hyperemisation of the skin — most of our measurements were made with the sensor at 42°, more recently some were made with the temperature increased to 43°. 22 premature babies in the Neonatal Unit at University College Hospital were monitored. All were undergoing oxygen therapy during treatment for respiratory disease. 13 of the subjects, aged 4 to 101 hours, had an umbilical artery catheter with a built in PO2 transducer, providing a means of continuous comparison of arterial with skin PO2 (the catheter-tip transducer has been used in more than 50 infants at U.C.H. and has been shown to give a linear response to PaO2 2,3).


Sick Neonate Sick Infant Arterial Trace Distressed Infant Umbilical Artery Catheter 
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  1. 1.
    P. Eberhard, W. Mindt, F. Jann and K. Hammacher. “Oxygen monitoring of newborns by skin electrodes. Correlation between arterial and cutaneously determined PO2” Advances in Experimental Medicine and Biology 37B 1097 (1973).CrossRefGoogle Scholar
  2. 2.
    D. Parker and L.P. Soutter. “In vivo monitoring of blood PO2 in newborn infants”. Proc. symposium on Current Status of Oxygen Measurements in Biology and Medicine, Marlow, June 1974. Butterworths (in press).Google Scholar
  3. 3.
    M. Conway, G.M. Durbin, D. Parker, E.O.R. Reynolds and L.P. Soutter. “Continuous measurement of arterial oxygen tension using a new-catheter-tip Polarographic electrode”. Proc. N.I.H. Conference on Perinatal Intensive Care, Bethesda (1974) edit J. Dancis (in press).Google Scholar
  4. 4.
    R. Huch, A. Huch and D.W. Lubbers. “Transcutaneous measurement of blood PO2 — Method and application in perinatal medicine”. J. Perinat. Med. 1 183 (1973).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Linda P. Soutter
    • 1
  • Dawood Parker
    • 1
  1. 1.Department of Medical PhysicsUniversity College HospitalLondonUK

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