A Comparison of Transcutaneous and Arterial PO2 in Sick Neonates
We have investigated the reliability of a transcutaneous PO2 sensor — the Hoffmann la Roche Oxygen Monitor 5300 — for the continuous assessment of the arterial PO2 of sick infants over periods of several hours. The PO2 transducer — developed by Eberhard and his colleagues — uses a large cathode 4 mm in diameter in conjunction with a membrane of low oxygen permeability to prevent alteration of the oxygen profile in the tissue by the oxygen consumption of the sensor. The transducer is heated to produce local hyperemisation of the skin — most of our measurements were made with the sensor at 42°, more recently some were made with the temperature increased to 43°. 22 premature babies in the Neonatal Unit at University College Hospital were monitored. All were undergoing oxygen therapy during treatment for respiratory disease. 13 of the subjects, aged 4 to 101 hours, had an umbilical artery catheter with a built in PO2 transducer, providing a means of continuous comparison of arterial with skin PO2 (the catheter-tip transducer has been used in more than 50 infants at U.C.H. and has been shown to give a linear response to PaO2 2,3).
KeywordsSick Neonate Sick Infant Arterial Trace Distressed Infant Umbilical Artery Catheter
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