Advertisement

The Measurement of Myocardial Microflow and Its Reaction to Hypoxia and Hypercapnia

  • K. Skolasinska
  • D. W. Lübbers
  • R. Wodick
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)

Abstract

Determination of moycaridal microcirculation was performed using chemically generated hydrogen (Lübbers and Stosseck 1970). With this measurement a tissue area is involved which is smaller than the average capillary supply volume. Thus, the usual representation of flow as flow/volume cannot be strictly applied. As Wodick (1973) has shown this method measures the flow which penetrates a perpendicular plane, therefore the flow is expressed as flow/area. The radius of this plane is approximately 150 um. Hydrogen coming from the generating “electrode” must pass through this theoretical plane, and the microflow is calculated as an intergrated value of flow velocity over the surface of this plane. To compare the flow/area with the flow/volume values we have to divide our value by the vessel lengths through which gas exchange can occur. Not being able to exactly determine the length of the vessels, we assume from a mean blood flow of 75 ml/100 g min a length of approximately 2.4 mm.

Keywords

Mean Arterial Blood Pressure Continuous Method Vessel Length Time Dependent Function Single Impulse 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Lubbers D. W., Stosseck, K.: Quantitative Bestimmung der lokalen Durchblutung durch elektrochemisch im Gewebe erzeugten Wasserstoff. Naturwissensch. 57, 311 – 312 (1970)CrossRefGoogle Scholar
  2. 2.
    Wodick, R.: Möglichkeiten und Grenzen der Bestimmung der Blutversorgung mit Hilfe der lokalen Wasserstoffclearance. Habilitationsschrift, Bochum 1973Google Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • K. Skolasinska
    • 1
  • D. W. Lübbers
    • 1
  • R. Wodick
    • 1
  1. 1.Max-Planck-Institut fur Systemphysiologie46 DortmundGerman Federal Republic

Personalised recommendations