Effect of a Shift of the Oxygen Dissociation Curve on Myocardial Oxygenation at Hypoxia

  • Z. Turek
  • F. Kreuzer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)


Krogh’s cylindrical model of the tissue (1922) has been widely used for the estimation of tissue oxygen tension (PO2). The model is based on several assumptions but it probably depicts the major trends in the changes of oxygen tension, even though the absolute values may deviate from reality.


Coronary Blood Flow Dissociation Curve Unfavorable Effect Severe Hypoxia Oxygen Affinity 
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  1. Adair, G.S.: J. biol. Chem. 63; 529, 1925.Google Scholar
  2. Duvelleroy, M.A., Mehmel, H., Laver, M.B.: J.Appl.Physiol. 35; 480, 1973.PubMedGoogle Scholar
  3. Kety, S.S.: Federation Proc. 16; 666, 1957.Google Scholar
  4. Krogh, A.: The Anatomy and Physiology of Capillaries, New Haven, Yale University Press, 1922.Google Scholar
  5. Rakušan, K.: Oxygen in the Heart Muscle, Springfield, Ill., C.C.Thomas, 1971.Google Scholar
  6. Roughton, F.J.W., Severinghaus, J.W.: J.Appl.Physiol. 35; 861, 1973.PubMedGoogle Scholar
  7. Rushmer, R.P.: Cardiovascular Dynamics, Philadelphia, Saunders, 1961.Google Scholar
  8. Thews, G.: Pflügers Arch. ges. Phys. 271; 197, 1960.CrossRefGoogle Scholar
  9. Turek, Z., Kreuzer, F., Hoofd, L.J.C.: Pflügers Arch. 342; 185, 1973.PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Z. Turek
    • 1
  • F. Kreuzer
    • 1
  1. 1.Department of Physiology, Faculty of MedicineUniversity of NijmegenNijmegenThe Netherlands

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