The Distribution of Oxygen Consumption Rates in Some Tissues before and after X-Irradiation

  • T. B. Constable
  • N. T. S. Evans
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)


The oxygen consumption rate per unit volume of tissue is one of the factors which determines tissue oxygen tension, the other factors being arterial tension, blood perfusion and the oxygen diffusion constant and solubility. Since the microscopic structure of tumours has an important role in the response to radiation there is a need for developing techniques for measuring the local distributions of these parameters.


Carbon Monoxide Oxygen Uptake Oxygen Consumption Rate Oxygen Uptake Rate Oxygen Equilibration 
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  1. 1.
    N.T.S. Evans and T.B. Constable. A method for measuring oxygen uptake rate distributions over the surface zone of excised tissue using a 91-cathode electrode. This symposium.Google Scholar
  2. 2.
    E.G. Ball, C.F. Strittmatter and O. Cooper. The reaction of cytochrome oxidase with carbon monoxide. J. Biol. Chem. , 193, 635–647 (1951).PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • T. B. Constable
    • 1
  • N. T. S. Evans
    • 1
  1. 1.Medical Research Council, Cyclotron UnitHammersmith HospitalLondonUK

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