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Effects of Dopamine and Epinephrine on Intestinal Blood Flow and Oxygen Uptake

  • W. W. Pawlik
  • A. P. Shepherd
  • D. Mailman
  • L. L. Shanbour
  • E. D. Jacobson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)

Abstract

The cardiovascular effects of dopamine (3,4-dihydroxyphenyl-ethylamine) have been studied by numerous investigators and because of its effects on splanchnic hemodynamics, dopamine has been suggested as a therapeutic agent in cardiovascular shock (1). In normal, anesthetized dogs and in shocked dogs, dopamine is a potent vasoconstrictor in the intestinal circulation (2,3), but the effects of dopamine on the delivery of oxygen to the gut are unknown.

Keywords

Oxygen Uptake Reduce Blood Flow Beta Adrenergic Blockade Intestinal Blood Flow Mesenteric Blood Flow 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Ulano, H. B., et al. Gastroenterology 62:39–47, 1972.PubMedGoogle Scholar
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    Shepherd, A. P., et al. Cire. Res. 33:166–174, 1973.CrossRefGoogle Scholar
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    Shepherd, A. P. and H. J. Granger. Gastroenterology 65:77–91, 1973.PubMedGoogle Scholar
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    Pawlik, W., et al. Gastroenterology 67:100–106, 1974.PubMedGoogle Scholar
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    Higgins, C. B., et al. Amer. J. Physiol. 225:432–437, 1973.PubMedGoogle Scholar
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    Pawlik, W., et al. Fed. Proc. 3:338, 1974 (Abstract).Google Scholar

Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • W. W. Pawlik
    • 1
    • 2
  • A. P. Shepherd
    • 1
    • 2
  • D. Mailman
    • 1
    • 2
  • L. L. Shanbour
    • 1
    • 2
  • E. D. Jacobson
    • 1
    • 2
  1. 1.Institute of PhysiologyMedical AcademyKrakowPoland
  2. 2.Departments of PhysiologyThe University of Texas Health Science CentersHouston & San AntonioUSA

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