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Effect of Ionizing Radiation on Liver Microcirculation and Oxygenation

  • H. I. Bicher
  • G. V. Dalrymple
  • D. Ashbrook
  • R. Smith
  • D. Harris
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)

Abstract

Ionizing radiation causes destruction of mammalian tissue by two mechanisms (11): 1) inhibition of the proliferative capacity of rapidly dividing cells, and 2) irreversible damage to elements of the microcirculatory system. Organs such as liver, kidney, and brain, not characterized by rapidly proliferating cells, exhibit a relatively pronounced radiosensitivity in spite of a very slow rate of cellular turnover. The radiosensitivity of the microcirculation could provide the reason for the radiosensitivity of the entire organ or tissue.

Keywords

Platelet Aggregation Platelet Adhesiveness Microcirculation Disturbance Microcirculatory System Photoelectric Method 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • H. I. Bicher
    • 1
    • 2
  • G. V. Dalrymple
    • 2
  • D. Ashbrook
    • 2
  • R. Smith
    • 1
  • D. Harris
    • 2
  1. 1.Department of PharmacologyUniversity or Arkansas Medical CenterLittle RockUSA
  2. 2.Department of RadiologyUniversity or Arkansas Medical CenterLittle RockUSA

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