A System for in Vivo Measurement of Oxygen in Intraocular Tissue

  • Robert W. Flower
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)


The sensory retina of the eye is unique in that it is nourished by the two separate circulations between which it lies—the retinal vasculature supplying the inner retinal layers and the choroidal vasculature supplying primarily the outer layers. The extremely high metabolic rate of retinal tissue makes it susceptible to ischemic damage when the retinal blood supply is segmentally or totally disrupted; the effect of interrupted choroidal blood supply is currently less well documented. Consequently, the relationship between individual contributions of the retinal and choroidal circulations to retinal oxygenation is fundamental to a thorough understanding of the physiology associated with ischemic eye disease. A number of investigators interested in intraocular oxygen distributions have applied the technique of Polarographic oxygen measurements using microelec-trodes1,2,3..., and one has even coined the convenient term “ophtha lmopolarography”.4


Electrode Pair Polarize Potential Hyperbaric Chamber Choroidal Circulation Current Monitor 


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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • Robert W. Flower
    • 1
  1. 1.The Applied Physics Laboratory and The Wilmer, Ophthalmological Institute of The Johns HopkinsUniversity and HospitalBaltimoreUSA

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