Oxygen Supply to the Open Rabbit Cornea

  • R. E. Barr
  • V. G. Murphy
  • E. L. Roetman
  • M. B. Hennessey
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 75)


The cornea is composed of three principal cellular layers, the epithelium, stroma and endothelium. Each layer requires oxygen in sufficient amount for aerobic metabolism to occur at some minimum level if normal corneal transparency is to be maintained over any extended time period. It has been well established that the surrounding limbal circulation supplies little, if any, oxygen to the central portion of the cornea. Thus, oxygen must be supplied from the atmosphere, in the case of an open eye, and/or the aqueous humor in the anterior chamber.


Oxygen Tension Anterior Chamber Aqueous Humor Corneal Surface Oxygen Flux 
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Copyright information

© Plenum Press, New York 1976

Authors and Affiliations

  • R. E. Barr
    • 1
  • V. G. Murphy
    • 1
  • E. L. Roetman
    • 1
  • M. B. Hennessey
    • 1
  1. 1.Departments of Ophthalmology & Mathematics, and The Dalton Research CenterUniversity of MissouriColumbiaUSA

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